Aperion Biologics Completes Enrollment in Z-Lig Anterior Cruciate Ligament Reconstruction Medical Device Performance Trial

28 March 2012

Aperion Biologics, Inc. announced that it has completed patient enrollment and implantation in the Company’s clinical trial of its Z-Lig Anterior Cruciate Ligament Reconstruction (ACLR) Device for the treatment of ligament injuries of the knee. The prospective, randomized and blinded multicenter study commenced in January 2011 in both Europe and South Africa to provide safety and performance data in the reconstruction of patients’ knees with primary ACL ruptures. The goal of the 60-patient study is to establish non-inferiority of the Z-Lig to allograft and the results will be used to support regulatory commercialization approvals and subsequent clinical acceptance of the Z-Lig ACLR device in select markets outside of the United States.